The XV. Symposium on Acute Cardiology and Emergency Medicine will be held as “Charité meets The Netherlands” addressing the growing Number of vulnerable Patients in the ED. The ED is recognized as Central Point of Contact, which enables the Direction of Patients in Specific Care Scenarios. With the Help of Digital Medicine, the ED evolves beyond the Exclusion of serious Disease to master all Acute Health Situations and initiate advance medical Therapies. We will discuss these Topics in the European International Perspective with a high-ranking Faculty of Guests from The Netherlands.